Reports of illegal chemicals being stored at the property have led to around 40 homes being evacuated in Bridlington.
Residents of Oxford Street are being told to pack an overnight bag after a bomb disposal team arrived at a property on the street.
Police executed a warrant this morning (Thursday August 4) as part of a pre-planned operation following reports of illegal chemicals being stored at the property.
A resident, who wished not to be named, told the Free Press that they were being told to go to The Spa, Bridlington if they had no alternative premises to go.
"The street has been cordened off by police and they are attempting to clear some of the road of vehicles," the resident said.
"Talking to the police, we might have to leave the premises for a considerable period of time. They have told us we could well be out of our homes for a minimum time of 24 hours.
"We have been told they will keep us up to date with any developments."
A 54-year-old man has been arrested and is assisting police with enquiries.
Specialist officers are in attendance as part of the warrant including the Explosive Ordnance Disposal (EOD).