Police said the crash on the A165 happened at around 12.30am this morning.
The road was closed between the park and ride roundabout, and the South Cliff roundabout while officers were at the scene.
It has now reopened.
Road reopens after serious collision in Scarborough
Motorists were this morning warned to avoid a major road in Scarborough following a collision.
By The Newsroom
Saturday, 28th October 2017, 10:49 am
Updated Tuesday, 12th December 2017, 1:15 pm