The incident, which occurred on the A64 junction with Cayton Low Road, near the Musham Bank roundabout, was reported by the Yorkshire Ambulance Service at 12.18am.
Enquiries are continuing to establish the full circumstances surrounding the death.
A 29-year-old local man has been arrested on suspicion of causing death by careless driving. He is currently being questioned in custody.
Diversions are still in place around the incident scene. Motorists are asked to avoid the area until further notice.
Anyone who was travelling along this road at around midnight and possibly may have information or dash-cam footage that could assist the investigation, is urged to call North Yorkshire
Police on 101, select option one, and speak to the force control room, quoting reference number 12200149402.