Newlands beat Division Two side Angel Reserves 4-1 to set up a Kenward Cup semi-final against fierce rivals Trafalgar.
Stew Bates hit a hat-trick for the victors, whose other goal came from their man of the match Jack Hakings.
Kurt Williamson scored Angel's solitary goal that levelled the game up, but the top flight side showed their class with three unanswered goals to seal the win.
Max Edwards shone at the back for Angel.
The winner of the Newlands v Trafalgar semi-final will meet Angel in the final after they beat Castle Tavern 4-0 in their last-four clash.
Cameron Dobson hit a hat-trick and Ben Mason grabbed their other goal.
Dan Jones' side didn't have much time to enjoy their cup victory as they then played another game against Ayton at the Flamingo Land Stadium in Division One.
Martin Cooper led the charge for Angel, who won 14-4, with five goals, Jackson Jowett also hitting a hat-trick, while keeper Joe Wright came outfield for the last 30 minutes and also hit a treble.
Ryan Somers, Macauley Youngson and Jamie Bradshaw got their other goals.
Arron Aghajanian was Ayton's star man as he scored two, while James Fox scored and Jazz Garvie also netted a penalty.
Following on from their NRCFA Sunday Challenge Cup success against Angel on Friday night, Trafalgar romped to a 16-0 win against West Pier.
Boss Col Jenkinson shuffled his pack from their cup final victory, Chris Dove leading their charge with five goals.
Mikey Barker followed up his brace on Friday night with a hat-trick, while Tyson Stubbings and Josh Young both hit two goals each.
Traf's other goals came from club stalwart Alex Sheader, Luke Jones and player-boss Jenkinson.
Skipper Tyler Richardson was their man of the match.
Hush claimed a 6-3 win against Ayton Reserves in Division Two.
Callum Myers led the Hush charge with four goals, striker Zac Hansen hitting their other two.
Ryan Link and Aidan McCallion were Hush's star men.
Player-boss Steven Frederiksen, Chris Hannam and Liam Scott were on the scoresheet for Ayton.
Midfielders Scott Davison and Jamie Heritage impressed for Ayton.