The incident happened at 5.10pm on May 26 and involved a white Ford Fiesta and a white Vauxhall van.
Two air ambulances attended the scene and after assessment, three casualties were taken by land ambulance to James Cook Hospital in Middlesbrough for treatment. Their injuries are not believed to be life-threatening.
Police are appealing for witnesses to the collision or anyone who recalls seeing the vehicles prior to the collision, to get in touch as soon as possible to assist the investigation.
Please quote reference number 12210125885.