Local MP, Robert Goodwill, will conduct the ceremony, which will also be attended by local councillors and representatives of the Environment Agency and contractor Balfour Beatty.
The scheme protects the main A174 route between Whitby and Sandsend where worn-out coastal defences have been replaced along a 1km stretch of the road where it runs parallel to the beach.
Work has been funded by £4.5m from North Yorkshire county council and £4.7m from the Department for the Environment, Food and Rural Affairs.
Mr Goodwill said: “I am delighted to see this major investment in my constituency to protect this vital stretch of coastline and the main road that runs alongside it. As well as protecting the environment, the work will benefit residents, visitors and the economy.”
To coincide with the ceremony, a drop-in exhibition detailing the work that has been carried out will be held at the Pyman Institute, Sandsend, between 9am and noon, when members of the public are invited to go to speak to members of the project team, who are keen to hear feedback on the completed project.